When Tomi Olusanya heard the news of the exit of GlaxoSmithKline from Nigeria, he was preparing to leave his work desk at the remote office from where he led the pharmacy operations at Wellahealth.
The pharmaceutical giant announced its decision to shut down operations in Nigeria shortly after the company’s shareholders asked the Federal Government to help salvage the company from the almost inevitable in their June 2023 AGM.
At the heart of the Wella Partner Program are over 2000+ pharmacies with nearly 200,000+ patients dependent on the business for their medications annually. Knowing that this exit would mark important changes in the prescription and retail pharmacy industry, Tomi sprung to action with his team.
The goal was simple. Develop small-bite learning content that explained active ingredients, discussed the GSK product in Nigeria, and shared alternatives with customers and the general public. These alternatives must have the same active ingredients to be recommended against existing GSK products to help the public adjust accordingly.
What is an active ingredient?
The active ingredient in a drug is the main component of that drug that enables it to “do what it says it will do”. According to the Australian Department of Health and Aged Care, It is the chemical compound in a drug that has an effect on the body.
To explain simply, I read tens of blogs to demystify active ingredients and explain them to the public. I found the response by the same organization above to be helpful
The active ingredient in a medicine enables the medicine to do what it claims. Examples of active ingredients are paracetamol in some pain relief medicines and atorvastatin in some cholesterol-lowering medicines.
Recommended read: Rosuvastatin Vs Atorvastatin
Generic Switching
The conversation around generic switching came up a lot after this announcement. Generic switching involves the prescription of a drug with the same active-ingredient formula as a brand-name drug. In the case of a GSK product, it would mean the prescription and/or dispensing of other drugs with the same active ingredients as the ones manufactured and/or distributed by GSK Nigeria.
Twitter users in the pharmaceutical industry began the conversation around Generic Switching. Here is what some of them said:
For Dr. Ikpeme Neto, Wellahealth will be looking more into generic switching:
Generic switching has always been a big drive for us at @WellaHealth. Now a more pressing initiative we will put more energy into, watch this space. https://t.co/If3RgBqxxV
— Neto – $healthsend.africa affiliate$ (@docneto) August 4, 2023
This position is consistent with a tweet he shared in 2020 on the cost of managing diabetes with brand-name products and how generic switching would help reduce the burden:
High cost of medications is the biggest barrier to adherence to therapy in diabetes. More generic switching and rational prescribing required. Interestingly, significant number of diabetics don’t have more than primary school education. Promoting self-care not easy.#MedLitclub pic.twitter.com/jtgsCVFSov
— Neto – $healthsend.africa affiliate$ (@docneto) December 4, 2020
Wefill Africa retweeted Aproko Pharmacist’s response to Frontline RX tweet, sharing some of the medications he’d advise patients using GSK Products to switch to as a result of the announcement:
It very sad
As for me
For Augmentin I will go for Lynxiclav or Fleming
Ampliclox – Reichlox
Amoxil- Reichmox
Ventolin- Aeroline
Zinnat – Roxirite
Voltaren – Neurogesic, I know not same compound.
Betnovate- Betasone N
Otrivin- Xylo-Acino
Duodart- TamdusterHopefully, we adjust
It very sad
As for me
For Augmentin I will go for Lynxiclav or Fleming
Ampliclox – Reichlox
Amoxil- Reichmox
Ventolin- Aeroline
Zinnat – Roxirite
Voltaren – Neurogesic, I know not same compound.
Betnovate- Betasone N
Otrivin- Xylo-Acino
Duodart- TamdusterHopefully, we adjust
— Aproko Pharmacist™ (@AprokoPhamacist) August 4, 2023
GSK Products and their alternatives
It took approximately 6 hours for Tomi and his team at Wellahealth to compile the list of alternative brands to branded GSK products.
Here is the list:
Active Ingredient | GSK Product | Alternative Brand 1 | Alternative Brand 2 |
Amoxicillin 500mg | Amoxil Beecham 500mg | Reichmox 500mg (Medreich) | Emmox 500mg (Emzor) |
Ampicillin-Cloxacillin 500mg | Ampiclox Beecham | Reichaclox 500mg (Medreich) | Vitaclox 500mg (Vitabiotics) |
Amoxicillin/Clavulanate | Augmentin | Fleming (Zentiva- Sanofi) | Amoksiclav (Glek) |
Dutasteride/Tamsulosin 0.5/0.4mg | Duodart | Dutasteride/Tamsulosin 0.5/0.4mg (Accord) | Duostam (Pharmacy plus) |
Dutasteride 0.5mg | Avodart | Dutasteride 0.5mg (Accord) | Dutasteride 0.5mg (Milpharm) |
Fluticasone (Spray) | Avamys Nasal Spray | Furamist spray (Cipla) | FlutifloFT (Lupin) |
Salbutamol (Spray) | Ventolin | Aeroline (Jewim) | Vitabiotics Salbutamol (Vitabiotics) |
Salmeterol/Fluticasone (Spray) | Seretide | Seroflo (Cipla) | Saltrol HFA (Getz) |
Clobetasol | Dermovate | Clobetasol (Actavis) | Tempovate cream (PT. Supra Ferbindo Farma) |
Levetiracetam | Keppra | Levitiracetam (Crescent) | Levewell 500mg (Wellona Pharma) |
Paroxetine | Seroxat | Paroxetine 20mg (Crescent) | Paroxetine 20mg (Medreich) |
Disclaimer: This is not an exhaustive list, as you should always speak to your attending pharmacy to discuss the alternative.
The departure of a big pharmaceutical company like GlaxoSmithKline Nigeria Limited may not be what Nigerians want to deal with at the moment. Patients are already seeing their essential medications and refills leave retail shelves as they become more difficult to stock. Other shelf regulars are becoming very expensive. Yet, bleak news like this might be an opportunity for local pharmaceutical product manufacturers and players to position and grow.
As Tomi thanked his teammates for the work they put in, he reminded them of the charge by the CEO to develop a solution to help doctors and pharmacists track medications that are readily available on community pharmacy shelves nationwide.
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